Transglutaminase 2 anticorps (AA 1-80)

N° du produit ABIN7217294

L’anticorps anti-Transglutaminase 2 Polyclonal Lapin est utilisé pour la détection de Transglutaminase 2 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour Transglutaminase 2 anticorps (AA 1-80) (ABIN7217294)

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Transglutaminase 2 anticorps

Épitope: AA 1-80

Fonction: TGase2 Polyclonal Antibody

Specificité: TGase2 Polyclonal Antibody detects endogenous levels of TGase2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the N-terminal region of human TGase2 at AA range: 1-80

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: TGase2

Sujet: Rabbit Anti-TGase2 Polyclonal Antibody,TGM2, Protein-glutamine gamma-glutamyltransferase 2, Tissue transglutaminase, Transglutaminase C, TG(C), TGC, TGase C, Transglutaminase H, TGase H, Transglutaminase-2, TGase-2,Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. Protein-glutamine gamma-glutamyltransferase 2 encoded by TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the protein-glutamine gamma-glutamyltransferase 2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.,Protein-glutamine gamma-glutamyltransferase 2

Poids moléculaire: observerd band 90kDa

ID gène: 7052

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling