TPP1 anticorps (AA 10-90)

N° du produit ABIN7231876

L’anticorps anti-TPP1 Polyclonal produit chez le Lapin a été validé pour WB et ELISA. Il convient pour la détection de TPP1 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour TPP1 anticorps (AA 10-90) (ABIN7231876)

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TPP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TPP1 anticorps

Épitope: AA 10-90

Fonction: TPP1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of TPP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human TPP1 protein at AA range: 10-90

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur TPP1

Antigène: TPP1 (Tripeptidyl Peptidase I (TPP1))

Autre désignation: TPP1

Sujet: Rabbit Anti-TPP1 Polyclonal Antibody,Tripeptidyl-peptidase 1, TPP-1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, TPP-I,TPP1 encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in TPP1 result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.,TPP1

Poids moléculaire: observerd band 61kDa

ID gène: 1200

UniProt: O14773

Pathways: Cycle Cellulaire, ER-Nucleus Signaling