Tuberin anticorps (pSer939)

N° du produit ABIN7224810

Cet anticorps Lapin Polyclonal détecte spécifiquement Tuberin dans ELISA, WB et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Tuberin anticorps (pSer939) (ABIN7224810)

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tuberin est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Tuberin anticorps

Épitope: pSer939

Fonction: Tuberin (phospho Ser939) Polyclonal Antibody

Specificité: Phospho-Tuberin (S939) Polyclonal Antibody detects endogenous levels of Tuberin protein only when phosphorylated at S939.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from human Tuberin Phospho-Ser939

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Tuberin

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Autre désignation: Tuberin

Sujet: Rabbit Anti-Tuberin (phospho Ser939) Polyclonal Antibody,TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein,Mutations in TSC2 (tuberous sclerosis 2) lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.,Tuberin

Poids moléculaire: observerd band 200kDa

ID gène: 7249

UniProt: P49815

Pathways: Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus