Tumor Protein p73 anticorps (pTyr99)
Aperçu rapide pour Tumor Protein p73 anticorps (pTyr99) (ABIN7213102)
Antigène
Voir toutes Tumor Protein p73 (TP73) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pTyr99
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Fonction
- p73 (phospho Tyr99) Polyclonal Antibody
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Specificité
- Phospho-p73 (Y99) Polyclonal Antibody detects endogenous levels of p73 protein only when phosphorylated at Y99.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human p73 Phospho-Tyr99
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Autre désignation
- p73
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Sujet
- Rabbit Anti-p73 (phospho Tyr99) Polyclonal Antibody,TP73, P73, Tumor protein p73, p53-like transcription factor, p53-related protein,TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that TP73 is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for TP73, but the biological validity and the full-length nature of some variants have not been determined.,Tumor protein p73
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Poids moléculaire
- observerd band 73kDa
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ID gène
- 7161
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UniProt
- O15350
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Pathways
- Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
Antigène
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