WISP3 anticorps (AA 1-50)

N° du produit ABIN7227052

Cet anticorps anti-WISP3 Polyclonal Lapin (ABIN7227052) détecte spécifiquement WISP3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour WISP3 anticorps (AA 1-50) (ABIN7227052)

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WISP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-WISP3 anticorps

Épitope: AA 1-50

Fonction: Rabbit Anti-WISP-3 Polyclonal Antibody

Specificité: The antibody detects endogenous WISP-3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthetic peptide from human protein at AA range: 1-50

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur WISP3

Antigène: WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

Autre désignation: WISP-3

Sujet: WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6WISP3 (WNT1 inducible signaling pathway protein 3) encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of WISP3 are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for WISP3.

Poids moléculaire: 55kD

ID gène: 8838

UniProt: O95389

Pathways: Signalisation WNT, Growth Factor Binding