Caspase 4 anticorps (AA 91-105)
Aperçu rapide pour Caspase 4 anticorps (AA 91-105) (ABIN7232775)
Antigène
Voir toutes Caspase 4 (CASP4) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 91-105
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Fonction
- Anti-Caspase-13 Rabbit Polyclonal Antibody
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Specificité
- This antibody recognizes human, mouse, and rat caspase-13 (43 kDa).
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Réactivité croisée
- Humain, Souris, Rat
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Immunogène
- Peptide corresponding to aa 91- 105 of human caspase-13 (accession no. O75601).
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Isotype
- IgG
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Indications d'application
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Immunoblotting: use at 1 μg/mL.
Immunohistochemistry: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.
Positive control: Whole cell lysate from HL60 cells. -
Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Dilute in PBS or medium which is identical to that used in the assay system.
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
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- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Autre désignation
- CASP13
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Sujet
- Caspase-13,Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-13 or ERICE (Evolutionarily Related Interleukin-1 Converting Enzyme) was recently described. When activated by caspase-8, caspase-13 induces apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.,CASP-13, EC 3.4.22.-, Evolutionary related interleukin-1-beta-converting enzyme, ERICE [Cleaved into: Caspase-13 subunit 1, Caspase-13 subunit 2]
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ID gène
- 338039
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NCBI Accession
- NP_788811
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UniProt
- O75601
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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