ABI1 anticorps (AA 180-230)

N° du produit ABIN7265359

Cet anticorps Lapin Polyclonal détecte spécifiquement ABI1 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour ABI1 anticorps (AA 180-230) (ABIN7265359)

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ABI1 anticorps

Épitope: AA 180-230

Fonction: ABI1 Rabbit pAb

Séquence: PMSGRGTLGR NTPYKTLEPV KPPTVPNDYM TSPARLGSQH SPGRTASLNQ R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 180-230 of human ABI1 (NP_001012770).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ABI1

Antigène: ABI1 (Abl-Interactor 1 (ABI1))

Autre désignation: ABI1

Sujet: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.,ABI1,ABI-1,ABLBP4,E3B1,NAP1BP,SSH3BP,SSH3BP1,Signal Transduction,G protein signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Growth factor,EGF,ABI1

Poids moléculaire: 35-55kDa

ID gène: 10006

UniProt: Q8IZP0

Pathways: Signalisation RTK, Response to Water Deprivation, ER-Nucleus Signaling