Calpain S1 anticorps
Aperçu rapide pour Calpain S1 anticorps (ABIN7266036)
Antigène
Voir toutes Calpain S1 (CAPNS1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Calpain small subunit 1 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Calpain small subunit 1
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Calpain S1 (CAPNS1) (Calpain, Small Subunit 1 (CAPNS1))
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Autre désignation
- CAPNS1
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Sujet
- This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],CALPAIN4, CANP, CANPS, CAPN4, CDPS, CSS1,Calcium Signaling,Immunology & Inflammation,Neuroscience,Signal Transduction,T Cell Receptor Signaling Pathway,CAPNS1
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Poids moléculaire
- 28kDa
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ID gène
- 826
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UniProt
- P04632
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Pathways
- Apoptose
Antigène
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