Cathepsin D anticorps
Aperçu rapide pour Cathepsin D anticorps (ABIN7266149)
Antigène
Voir toutes Cathepsin D (CTSD) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Cathepsin D Rabbit mAb
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Cathepsin D .
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cathepsin D (CTSD)
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Autre désignation
- CTSD
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Sujet
- This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],CLN10;CPSD;HEL-S-130P;Cathepsin D;CTSD,Cancer,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Invasion and Metastasis,Neuroscience,Signal Transduction,Ubiquitin,CTSD
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Poids moléculaire
- 46kDa/28kDa
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ID gène
- 1509
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Antigène
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