CAND1 anticorps (AA 750-980)

N° du produit ABIN7266546

Détail du produit anti-CAND1 anticorps

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Épitope: AA 750-980

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAND1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: CAND1 Rabbit pAb

Séquence: GALSAMLDFF QALVVTGTNN LGYMDLLRML TGPVYSQSTA LTHKQSYYSI AKCVAALTRA CPKEGPAVVG QFIQDVKNSR STDSIRLLAL LSLGEVGHHI DLSGQLELKS VILEAFSSPS EEVKSAASYA LGSISVGNLP EYLPFVLQEI TSQPKRQYLL LHSLKEIISS ASVVGLKPYV ENIWALLLKH CECAEEGTRN VVAECLGKLT LIDPETLLPR LKGYLISGSS Y

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 750-980 of human CAND1 (NP_060918.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CAND1

Antigène: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Autre désignation: CAND1 (CAND1 Produits)

Synonymes: anticorps TIP120, anticorps TIP120A, anticorps ATCAND1, anticorps CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1, anticorps ETA2, anticorps HEMIVENATA, anticorps HVE, anticorps T8K22.14, anticorps T8K22_14, anticorps cullin-associated and neddylation dissociated, anticorps Tip120, anticorps Tip120A, anticorps fb78a05, anticorps wu:fb78a05, anticorps zgc:55729, anticorps tip120, anticorps tip120a, anticorps cand2, anticorps 2310038O07Rik, anticorps 6330512O03Rik, anticorps AI195005, anticorps AI846556, anticorps D10Ertd516e, anticorps Tp120a, anticorps mKIAA0829, anticorps cullin associated and neddylation dissociated 1, anticorps cullin-associated and neddylation dissociated, anticorps cullin-associated and neddylation-dissociated 1, anticorps cullin-associated and neddylation-dissociated 1 L homeolog, anticorps cullin-associated NEDD8-dissociated protein 1, anticorps cullin associated and neddylation disassociated 1, anticorps CAND1, anticorps Cand1, anticorps cand1, anticorps cand1.L, anticorps LOC100159824, anticorps LOC100177977

Sujet: This gene encodes an essential regulator of Cullin-RING ubiquitin ligases, which are in involved in ubiquitinylation of proteins degraded by the Ub proteasome system. The encoded protein binds to unneddylated cullin-RING box protein complexes and acts as an inhibitor of cullin neddylation and of Skp1, cullin, and F box ubiquitin ligase complex assembly and activity. In mammalian cell culture, this protein predominantly localizes to the cytoplasm. Knockdown of this gene in preadipocytes results in blocked adipogenesis. Alternative splicing results in multiple transcript variants.,CAND1,TIP120,TIP120A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,CAND1

Poids moléculaire: 45kDa/117kDa/136kDa

ID gène: 55832

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization