CISH anticorps (AA 17-130)

N° du produit ABIN7266663

Cet anticorps anti-CISH est un anticorps Lapin Polyclonal détectant CISH dans WB et IF. Adapté pour Humain.

Aperçu rapide pour CISH anticorps (AA 17-130) (ABIN7266663)

Antigène: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CISH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CISH anticorps

Épitope: AA 17-130

Fonction: CISH Rabbit pAb

Séquence: TGQRPLWAPS LELPKPVMQP LPAGAFLEEV AEGTPAQTES EPKVLDPEED LLCIAKTFSY LRESGWYWGS ITASEARQHL QKMPEGTFLV RDSTHPSYLF TLSVKTTRGP TNVR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CISH

Antigène: CISH (Cytokine Inducible SH2-Containing Protein (CISH))

Autre désignation: CISH

Sujet: The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.,CISH,BACTS2,CIS,CIS-1,G18,SOCS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,CISH

Poids moléculaire: 28kDa/29kDa/30kDa

ID gène: 1154

UniProt: Q9NSE2

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus