Dihydrofolate Reductase anticorps
Aperçu rapide pour Dihydrofolate Reductase anticorps (ABIN7266764)
Antigène
Voir toutes Dihydrofolate Reductase (DHFR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- DHFR Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human DHFR
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dihydrofolate Reductase (DHFR)
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Autre désignation
- DHFR
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Sujet
- Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014],DHFRP1, DYR,Amino acid metabolism,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Nucleotide metabolism,Signal Transduction,DHFR
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Poids moléculaire
- 21kDa
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ID gène
- 1719
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UniProt
- P00374
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Pathways
- Mitotic G1-G1/S Phases
Antigène
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