FADD anticorps

N° du produit ABIN7267134

Cet anticorps anti-FADD Monoclonal Lapin (ABIN7267134) détecte spécifiquement FADD dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FADD anticorps (ABIN7267134)

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FADD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FADD anticorps

Fonction: FADD Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human FADD

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FADD

Antigène: FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))

Autre désignation: FADD

Sujet: The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008],GIG3,MORT1,FADD,FADD,Apoptosis,Apoptosis_Death receptors & ligands,Apoptosis_Inhibition of Apoptosis,Apoptosis_Mitochondrial Control of Apoptosis,Cancer,Cell Biology & Developmental Biology,Death Receptor Signaling Pathway,Immunology & Inflammation,Invasion and Metastasis,Neurodegenerative Diseases,Neuroscience,Protein phosphorylation,Toll-like Receptor Signaling Pathway,FADD

Poids moléculaire: 28kDa

ID gène: 8772

UniProt: Q13158

Pathways: Apoptose, Signalisation TLR, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades