FGFR3 anticorps

N° du produit ABIN7267191

Détail du produit anti-FGFR3 anticorps

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: FGFR3 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human FGFR3

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: FGFR3 (FGFR3 Produits)

Synonymes: anticorps FGFR3, anticorps LOC100034114, anticorps ACH, anticorps CD333, anticorps CEK2, anticorps HSFGFR3EX, anticorps JTK4, anticorps FR3, anticorps Fgfr-3, anticorps Flg-2, anticorps HBGFR, anticorps Mfr3, anticorps sam3, anticorps fc27h01, anticorps wu:fc27h01, anticorps fibroblast growth factor receptor 3, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog, anticorps FGFR3, anticorps fgfr3.S, anticorps Fgfr3, anticorps fgfr3

Sujet: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009],ACH,CD333,CEK2,HSFGFR3EX,JTK4,FGFR3,Angiogenesis,Cancer,Cardiovascular,CDs,Cell Biology & Developmental Biology,ESC Pluripotency and Differentiation,Growth factors,Immunology & Inflammation,Kinase,Kinase_Tyrosine kinases,Neural Stem Cells,Signal Transduction,Stem Cells,FGFR3

Poids moléculaire: 98kDa

ID gène: 2261

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding