FGD1 anticorps (AA 700-800)

N° du produit ABIN7267284

Cet anticorps anti-FGD1 est un anticorps Lapin Polyclonal détectant FGD1 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour FGD1 anticorps (AA 700-800) (ABIN7267284)

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-FGD1 anticorps

Épitope: AA 700-800

Fonction: FGD1 Rabbit pAb

Séquence: LLNSTNREDE DTPPNSPNVD LGKRAPTPIR EKEVTMCMRC QEPFNSITKR RHHCKACGHV VCGKCSEFRA RLVYDNNRSN RVCTDCYVAL HGVPGSSPAC S

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FGD1 (NP_004454.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FGD1

Antigène: FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))

Autre désignation: FGD1

Sujet: This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.,FGD1,AAS,FGDY,MRXS16,ZFYVE3,FYVE,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,FGD1

Poids moléculaire: 106kDa

ID gène: 2245

UniProt: P98174

Pathways: Neurotrophin Signaling Pathway