GIT2 anticorps (AA 450-510)

N° du produit ABIN7267315

Cet anticorps Lapin Polyclonal détecte spécifiquement GIT2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour GIT2 anticorps (AA 450-510) (ABIN7267315)

Antigène: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIT2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GIT2 anticorps

Épitope: AA 450-510

Fonction: GIT2 Rabbit pAb

Séquence: ASRLEKQNST PESDYDNTPN DMEPDGMGSS RKGRQRSMVW PGDGLVPDTA EPHVAPSPTL P

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 450-510 of human GIT2 (NP_476511.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GIT2

Antigène: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Autre désignation: GIT2

Sujet: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.,GIT2,CAT-2,CAT2,PKL,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Cell Biology & Developmental Biology,Cytoskeleton,Actins,GIT2

Poids moléculaire: 52kDa, 70-84kDa

ID gène: 9815

UniProt: Q14161

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling