HDAC1 anticorps
Aperçu rapide pour HDAC1 anticorps (ABIN7267707)
Antigène
Voir toutes HDAC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Fonction
- [KO Validated] HDAC1 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human HDAC1.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- HDAC1 (Histone Deacetylase 1 (HDAC1))
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Autre désignation
- HDAC1
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Sujet
- Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],GON-10,HD1,RPD3,RPD3L1,HDAC1,Apoptosis,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Deacetylation,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Heart,Heart_Hypertrophy,Immunology & Inflammation,Neurodegenerative Diseases,Neuroscience,NF-kB Signaling Pathway,Notch Signaling Pathway,Nuclear Receptor Signaling,Signal Transduction,Stem Cells,Wnt/β-Catenin Signaling Pathway,HDAC1
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Poids moléculaire
- 55kDa
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ID gène
- 3065
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UniProt
- Q13547
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Pathways
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
Antigène
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