IGF1R anticorps (pTyr1131, pTyr1146)

N° du produit ABIN7267901

L’anticorps Lapin Polyclonal anti-IGF1R a été validé pour WB. Il convient pour détecter IGF1R dans des échantillons de Humain.

Aperçu rapide pour IGF1R anticorps (pTyr1131, pTyr1146) (ABIN7267901)

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGF1R est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IGF1R anticorps

Épitope: pTyr1131, pTyr1146

Fonction: Phospho-INSR-Y1146/IGF1R-Y1131 Rabbit pAb

Réactivité croisée: Humain

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around Y1146 of human INSR and Y1131 of human IGF1R.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IGF1R

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Autre désignation: IGF1R/INSR

Sujet: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],INSR/IGF1R,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,IGF1R/INSR

Poids moléculaire: 155kDa

ID gène: 3643, 3480

UniProt: P06213, P08069

Pathways: Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy