KIFAP3 anticorps

N° du produit ABIN7268120

L’anticorps Lapin Monoclonal anti-KIFAP3 a été validé pour WB et IF. Il convient pour détecter KIFAP3 dans des échantillons de Humain.

Aperçu rapide pour KIFAP3 anticorps (ABIN7268120)

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp KIFAP3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-KIFAP3 anticorps

Fonction: KIFAP3 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human KIFAP3

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KIFAP3

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Autre désignation: KIFAP3

Sujet: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011],FLA3, KAP-1, KAP-3, KAP3, SMAP, Smg-GDS, dJ190I16.1,Epigenetics & Nuclear Signaling,KIFAP3

Poids moléculaire: 91-100kDa

ID gène: 22920

UniProt: Q92845

Pathways: Signalisation Hedgehog, Sensory Perception of Sound