MAP2K6 anticorps

N° du produit ABIN7268643

Cet anticorps anti-MAP2K6 Monoclonal Lapin (ABIN7268643) détecte spécifiquement MAP2K6 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAP2K6 anticorps (ABIN7268643)

Antigène: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MAP2K6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K6 anticorps

Fonction: MEK3/MEK6 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human MEK3/MEK6

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MAP2K6

Antigène: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Autre désignation: MAP2K3/MAP2K6

Sujet: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008],MAPKK3, MEK3, MKK3, PRKMK3, SAPKK-2, SAPKK2,Protein phosphorylation,MAP2K3/MAP2K6

Poids moléculaire: 39,37kDa

ID gène: 5606, 5608

UniProt: P46734, P52564

Pathways: Signalisation MAPK, Signalisation TLR, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades