MAP2K7 anticorps
Aperçu rapide pour MAP2K7 anticorps (ABIN7268645)
Antigène
Voir toutes MAP2K7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- MEK7 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human MEK7
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
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Autre désignation
- MAP2K7
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Sujet
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],JNKK2, MAPKK7, MEK, MEK 7, MKK7, PRKMK7, SAPKK-4, SAPKK4,B Cell Receptor Signaling Pathway,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytoskeleton,Cytoskeleton_Actins,Death Receptor Signaling Pathway,Endocrine & Metabolism,ErbB-HER Signaling Pathway,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Innate Immunity_TLR Signaling,Kinase,MAPK-JNK Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Protein phosphorylation,Signal Transduction,T Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,MAP2K7
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Poids moléculaire
- 47kDa
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ID gène
- 5609
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UniProt
- O14733
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Pathways
- Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
Antigène
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