L’anticorps Lapin Polyclonal anti-MAPKAP Kinase 3 a été validé pour WB et IF. Il convient pour détecter MAPKAP Kinase 3 dans des échantillons de Humain.
N° du produit ABIN7268666
Aperçu rapide pour MAPKAP Kinase 3 anticorps (AA 1-240) (ABIN7268666)
MAPKAPK3
Reactivité: Souris
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
MAPKAP Kinase 3 (MAPKAPK3)
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
Autre désignation
MAPKAPK3
Sujet
This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.,MAPKAPK3,3PK,MAPKAP-K3,MAPKAP3,MAPKAPK-3,MDPT3,MK-3,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Microtubules,Immunology & Inflammation,MAPKAPK3