NAIP anticorps (AA 750-850)

N° du produit ABIN7268932

Cet anticorps Lapin Polyclonal détecte spécifiquement NAIP dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour NAIP anticorps (AA 750-850) (ABIN7268932)

Antigène: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAIP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NAIP anticorps

Épitope: AA 750-850

Fonction: NAIP Rabbit pAb

Séquence: LLRSIHFPIR GNKTSPRAHF SVLETCFDKS QVPTIDQDYA SAFEPMNEWE RNLAEKEDNV KSYMDMQRRA SPDLSTGYWK LSPKQYKIPC LEVDVNDIDV V

Réactivité croisée: Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human NAIP (NP_075043.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NAIP

Antigène: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Autre désignation: NAIP

Sujet: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length, additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,NAIP,BIRC1,NLRB1,psiNAIP,Cell Biology & Developmental Biology,Apoptosis,NAIP

ID gène: 4671

UniProt: Q13075

Pathways: Apoptose, Inflammasome