RHBDD1 anticorps (AA 206-315)

N° du produit ABIN7269978

Cet anticorps anti-RHBDD1 est un anticorps Lapin Polyclonal détectant RHBDD1 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour RHBDD1 anticorps (AA 206-315) (ABIN7269978)

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHBDD1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RHBDD1 anticorps

Épitope: AA 206-315

Fonction: RHBDD1 Rabbit pAb

Séquence: TQGPLKKIME ACAGGFSSSV GYPGRQYYFN SSGSSGYQDY YPHGRPDHYE EAPRNYDTYT AGLSEEEQLE RALQASLWDR GNTRNSPPPY GFHLSPEEMR RQRLHRFDSQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 206-315 of human RHBDD1 (NP_115652.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RHBDD1

Antigène: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Autre désignation: RHBDD1

Sujet: Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion, inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis, modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis, inhibits apoptotic activity in spermatogonia.,RHBDD1,RRP4,Cell Biology & Developmental Biology,Apoptosis,RHBDD1

Poids moléculaire: 12kDa/35kDa

ID gène: 84236

UniProt: Q8TEB9