SGPL1 anticorps (AA 60-390)

N° du produit ABIN7270533

Détail du produit anti-SGPL1 anticorps

Antigène: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Épitope: AA 60-390

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGPL1 est non-conjugé

Application: Western Blotting (WB)

Fonction: SGPL1 Rabbit pAb

Séquence: VFQPESLWSR FKKKCFKLTR KMPIIGRKIQ DKLNKTKDDI SKNMSFLKVD KEYVKALPSQ GLSSSAVLEK LKEYSSMDAF WQEGRASGTV YSGEEKLTEL LVKAYGDFAW SNPLHPDIFP GLRKIEAEIV RIACSLFNGG PDSCGCVTSG GTESILMACK AYRDLAFEKG IKTPEIVAPQ SAHAAFNKAA SYFGMKIVRV PLTKMMEVDV RAMRRAISRN TAMLVCSTPQ FPHGVIDPVP EVAKLAVKYK IPLHVDACLG GFLIVFMEKA GYPLEHPFDF RVKGVTSISA DTHKYGYAPK GSSLVLYSDK KYRNYQFFVD TDWQGGIYAS P

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 60-390 of human SGPL1 (NP_003892.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SGPL1

Antigène: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Autre désignation: SGPL1 (SGPL1 Produits)

Synonymes: anticorps SGPL1, anticorps zgc:162153, anticorps AI428538, anticorps D10Xrf456, anticorps S1PL, anticorps Spl, anticorps SPL, anticorps Spgl1, anticorps spl, anticorps sphingosine-1-phosphate lyase 1, anticorps sphingosine-1-phosphate lyase 1 L homeolog, anticorps sphingosine phosphate lyase 1, anticorps SGPL1, anticorps sgpl1.L, anticorps sgpl1, anticorps Sgpl1

Sujet: Cleaves phosphorylated sphingoid bases (PSBs, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Required for global lipid homeostasis in liver and cholesterol homeostasis in fibroblasts. Involved in the regulation of pro-inflammatory response and neutrophil trafficking. Modulates neuronal autophagy via phosphoethanolamine production which regulates accumulation of aggregate-prone proteins such as APP (By similarity. Seems to play a role in establishing neuronal contact sites and axonal maintenance (By similarity.,SGPL1,S1PL,SPL,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,SGPL1

Poids moléculaire: 63kDa

ID gène: 8879

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling