14-3-3 sigma/SFN anticorps
Aperçu rapide pour 14-3-3 sigma/SFN anticorps (ABIN7270602)
Antigène
Voir toutes 14-3-3 sigma/SFN (SFN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- 14-3-3 sigma Rabbit mAb
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human 14-3-3 sigma
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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Autre désignation
- SFN
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Sujet
- Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.,YWHAS,Cell Biology & Developmental Biology,Cell Cycle,Cell Type Marker,Cell Type Marker_Neuron marker,Cell Type Marker_Synapse marker,Epigenetics & Nuclear Signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Neuroscience,Signal Transduction,Stem Cells,SFN
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Poids moléculaire
- 28kDa
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ID gène
- 2810
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UniProt
- P31947
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Pathways
- Signalisation p53, Myometrial Relaxation and Contraction
Antigène
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