WASF1 anticorps (C-Term)

N° du produit ABIN7271345

L’anticorps Lapin Polyclonal anti-WASF1 a été validé pour WB. Il convient pour détecter WASF1 dans des échantillons de Humain.

Aperçu rapide pour WASF1 anticorps (C-Term) (ABIN7271345)

Antigène: WASF1 (WAS Protein Family, Member 1 (WASF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WASF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-WASF1 anticorps

Épitope: C-Term

Fonction: WASF1 Rabbit pAb

Séquence: VARAAPVCET VPVHPLPQGE VQGLPPPPPP PPLPPPGIRP SSPVTVTALA HPPSGLHPTP STAPGPHVPL MPPSPPSQVI PASEPKRHPS TLPVISDARS VLLEAIRKGI QLRKVEEQRE QEAKHERIEN DVATILSRRI AVEYSDSEDD SEFDEVDWLE

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur WASF1

Antigène: WASF1 (WAS Protein Family, Member 1 (WASF1))

Autre désignation: WASF1

Sujet: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.,WASF1,SCAR1,WAVE,WAVE1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Extracellular Matrix,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Neuroscience,WASF1

Poids moléculaire: 61kDa

ID gène: 8936

UniProt: Q92558

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization