L’anticorps anti-LRPPRC Polyclonal produit chez le Lapin a été validé pour IHC et IF. Il convient pour la détection de LRPPRC dans des échantillons provenant de Humain, Souris et Rat.
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LRPPRC,CLONE-23970,GP130,LRP130,LSFC,This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.