eIF4EBP1 anticorps

N° du produit ABIN7384405

Cet anticorps anti-eIF4EBP1 est un anticorps Lapin Monoclonal détectant eIF4EBP1 dans WB et IHC (p). Adapté pour Humain, Souris, Rat et Hamster.

Aperçu rapide pour eIF4EBP1 anticorps (ABIN7384405)

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp eIF4EBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R06-8E6

Détail du produit anti-eIF4EBP1 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur eIF4EBP1

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Autre désignation: 4E BP1

Sujet: 4E-BP1,4EBP1,4EBP1,BP 1,eIF4E binding protein 1,eIF4E-binding protein 1,Eif4ebp1,Eukaryotic translation initiation factor 4E-binding protein 1,PHAS-I,PHASI,Phosphorylated heat- and acid-stable protein regulated by insulin 1,Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1),is a member of 4EBPs family,which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E,thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors,hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1,alpha,beta and gamma.

Poids moléculaire:

Observed_MW: 15/20kDa

Calculated_MW: 13kDa

ID gène: 1978

UniProt: Q13541

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling