FAS anticorps

N° du produit ABIN7384441

Cet anticorps anti-FAS est un anticorps Lapin Monoclonal détectant FAS dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour FAS anticorps (ABIN7384441)

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FAS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: R02-8I7

Détail du produit anti-FAS anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FAS

Antigène: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Autre désignation: Fas

Sujet: ALPS 1A,ALPS1A,APO 1,Apo 1 antigen,APO 1 cell surface antigen,Apo-1 antigen,APO1,Apo1 antigen,APO1 cell surface antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,APT 1,APT1,CD 95,CD 95 antigen,CD95,CD95 antigen,Delta Fas,Delta Fas/APO 1/CD95,Delta Fas/APO1/CD95,Fas (TNF receptor superfamily,member 6),FAS 1,FAS 827dupA,Fas AMA,Fas,FAS Antigen,Fas cell surface death receptor,FAS1,FASLG receptor,FASTM,sFAS,Surface antigen APO1,TNF receptor superfamily,member 6,TNFRSF 6,TNFRSF6,TNR6,Tumor necrosis factor receptor superfamily member 6,FAS,also named as CD95,APO-1,APT1,FAS1 and TNFRSF6,is a receptor for TNFSF6/FASLG. It is a cell surface receptor belonging to the TNF receptor superfamily,can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). This anti-Fas monoclonal antibody can be used to induce apoptosis in cell cultures through Fas by imitating the Fas-ligand.

Poids moléculaire:

Observed_MW: 45kDa

Calculated_MW: 38kDa

ID gène: 355

UniProt: P25445

Pathways: Signalisation p53, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity