MCM2 anticorps

N° du produit ABIN7384466

Cet anticorps Lapin Monoclonal détecte spécifiquement MCM2 dans WB et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MCM2 anticorps (ABIN7384466)

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MCM2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: R08-9H4

Détail du produit anti-MCM2 anticorps

Purification: Affinity Purified

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Concentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MCM2

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Autre désignation: MCM2

Sujet: BM28,CCNL 1,CCNL1,CDC like 1,cdc19,CDCL 1,CDCL1,Cell devision cycle like 1,Cyclin like 1,D3S3194,DNA replication licensing factor MCM2,KIAA0030,MCM 2,MCM2,MCM2 minichromosome maintenance deficient 2 mitotin,MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae),MCM2 minichromosome maintenance deficient 2,mitotin,MCM2,MGC10606,Minichromosome maintenance complex component 2,Minichromosome maintenance deficient 2 (mitotin),Minichromosome maintenance deficient 2 mitotin,Minichromosome maintenance protein 2,Minichromosome maintenance protein 2 homolog,Mitotin,Nuclear protein BM28,OTTHUMP00000216047,OTTHUMP00000216050,The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with mCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. 

Poids moléculaire:

Observed_MW: 125kDa

Calculated_MW: 102kDa

ID gène: 4171

UniProt: P49736

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA