eIF4EBP1 anticorps (C-Term)
Aperçu rapide pour eIF4EBP1 anticorps (C-Term) (ABIN7448395)
Antigène
Voir toutes eIF4EBP1 (EIF4EBP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Rabbit anti-4EBP1 IHC Antibody, Affinity Purified
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Homologie
- Rat,Rabbit,Pig,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Thirteen-lined ground squirrel,Crab-eating macaque
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Purification
- Affinity Purified
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Immunogène
- Between AA 75 and C-term
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Isotype
- IgG
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Indications d'application
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
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Autre désignation
- 4EBP1
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Sujet
- Background: Eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) binds directly to eIF4E to inhibit complex assembly for translation initiation. 4EBP1 is part of a family of translation repressor proteins. 4EBP1 is directly phosphorylated by the mTORC1 complex during growth factor stimulation of cells. Phosphorylation of 4EBP1 causes its release from eIF4E to allow translation to proceed.
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ID gène
- 1978
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NCBI Accession
- NP_004086
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UniProt
- Q13541
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Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling
Antigène
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