BCAR1 anticorps (AA 275-325)

N° du produit ABIN7448429

L’anticorps anti-BCAR1 Polyclonal Lapin est utilisé pour la détection de BCAR1 dans des échantillons de Humain et Souris. Il a été validé pour IHC.

Aperçu rapide pour BCAR1 anticorps (AA 275-325) (ABIN7448429)

Antigène: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCAR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-BCAR1 anticorps

Épitope: AA 275-325

Fonction: Rabbit anti-BCAR1/p130CAS IHC Antibody, Affinity Purified

Homologie: Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 275 and 325

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BCAR1

Antigène: BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))

Autre désignation: BCAR1/p130CAS

Sujet: Background: BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells.

ID gène: 9564

NCBI Accession: NP_055382

UniProt: P56945

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling