COPS5 anticorps (AA 175-225)

N° du produit ABIN7448494

Cet anticorps Lapin Polyclonal détecte spécifiquement COPS5 dans IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour COPS5 anticorps (AA 175-225) (ABIN7448494)

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS5 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-COPS5 anticorps

Épitope: AA 175-225

Fonction: Rabbit anti-CSN5 IHC Antibody, Affinity Purified

Homologie: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Chimpanzee,Medaka fish,Atlantic salmon,Rainbow trout,Tasmanian devil,Nile tilapia,White-tufted-ear marmoset,Crab-eating macaque,Duckbill platypus,Pipidae,West Indian ocean coelacanth,Green anole,Gray short-tailed opossum,Japanese pufferfish,Small-eared galago,African elephant,Chinese hamster,European seabass,Naked mole rat,Thirteen-lined ground squirrel,Rainbow smelt,Little brown bat,Giant tiger prawn,Three-spined stickleback,Northern white-cheeked gibbon,Starlet sea anemone,Spotted green pufferfish,Zebra finch

Purification: Affinity Purified

Immunogène: Between AA 175 and 225

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur COPS5

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Autre désignation: CSN5

Sujet: Background: CSN5 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. CSN also possesses kinase activity. CSN5 has been identified as the subunit that functions to remove Nedd8, an ubiquitin-like modifier, from cullin-based E3-ubiquitin ligases. CSN5 also functions as a coactivator of nuclear receptors. COP9 signalsome complex subunit 5, signalsome subunit 5, SGN5, jun activation domain-protein 1, COPS5, JAB1, MOV-34, MGC3149.

ID gène: 10987

NCBI Accession: NP_006828

UniProt: Q92905

Pathways: Cycle Cellulaire