FEN1 anticorps (AA 250-300)

N° du produit ABIN7448564

L’anticorps Lapin Polyclonal anti-FEN1 a été validé pour IHC. Il convient pour détecter FEN1 dans des échantillons de Humain.

Aperçu rapide pour FEN1 anticorps (AA 250-300) (ABIN7448564)

Antigène: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FEN1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FEN1 anticorps

Épitope: AA 250-300

Fonction: Rabbit anti-Fen1 IHC Antibody, Affinity Purified

Homologie: Sheep,Bovine,Horse,Pig,Panda,Orangutan,Gorilla,Chimpanzee,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Little brown bat,Northern white-cheeked gibbon,Chinese hamster

Purification: Affinity Purified

Immunogène: Between AA 250 and 300

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 500 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur FEN1

Antigène: FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))

Autre désignation: Fen1

Sujet: Background: Flap endonuclease 1 (Fen1) is a member of the XPG/RAD2 endonuclease family. Fen1 functions primarily as an endonuclease that removes 5'-overhangs during base-excision DNA repair and lagging strand DNA synthesis. For these processes Fen1 interacts with PCNA and the 9-1-1 DNA repair complex. Fen1 also possesses 5' to 3' exonuclease activity as well as RNase H activity.

ID gène: 2237

NCBI Accession: NP_004102

UniProt: P39748

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA