KDM4A anticorps (AA 350-400)

N° du produit ABIN7448617

Cet anticorps Lapin Polyclonal détecte spécifiquement KDM4A dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour KDM4A anticorps (AA 350-400) (ABIN7448617)

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4A est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-KDM4A anticorps

Épitope: AA 350-400

Fonction: Rabbit anti-JMJD2A IHC Antibody, Affinity Purified

Homologie: Orangutan,Gorilla,Chimpanzee,White-tufted-ear marmoset,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KDM4A

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Autre désignation: JMJD2A

Sujet: Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.

ID gène: 9682

NCBI Accession: NP_055478

UniProt: O75164

Pathways: L'effet Warburg