MCM2 anticorps (pSer53)

N° du produit ABIN7448649

Cet anticorps anti-MCM2 Polyclonal Lapin (ABIN7448649) détecte spécifiquement MCM2 dans IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MCM2 anticorps (pSer53) (ABIN7448649)

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM2 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MCM2 anticorps

Épitope: pSer53

Fonction: Rabbit anti-Phospho MCM2 (S53) IHC Antibody, Affinity Purified

Homologie: Rat,Zebrafish,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,West Indian ocean coelacanth,Naked mole rat,Duckbill platypus,White-tufted-ear marmoset,Crab-eating macaque,Tasmanian devil,Florida lancelet,Small-eared galago,Three-spined stickleback,Chinese hamster,Zebra finch,Green anole,Little brown bat,Medaka fish,Nile tilapia,African elephant,Gray short-tailed opossum,Atlantic salmon

Purification: Affinity Purified

Immunogène: Surrounding serine 53

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MCM2

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Autre désignation: MCM2

Sujet: Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.

ID gène: 4171

NCBI Accession: NP_004517

UniProt: P49736

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA