MCM5 anticorps (AA 1-50)

N° du produit ABIN7448655

Cet anticorps anti-MCM5 est un anticorps Lapin Polyclonal détectant MCM5 dans IHC. Adapté pour Humain et Souris.

Aperçu rapide pour MCM5 anticorps (AA 1-50) (ABIN7448655)

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MCM5 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-MCM5 IHC Antibody, Affinity Purified

Homologie: X. laevis,Orangutan,Chimpanzee,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogène: Between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5

Sujet: Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM5 can form a subcomplex with MCM3. MCM5 also appears to play a role in transcription. MCM5 has been shown to interact with the signal transducer and activator of transcription 1 (STAT1) and demonstrated to be essential for STAT1 target gene transcription.

ID gène: 4174

NCBI Accession: NP_006730

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA