PML anticorps (AA 375-425)

N° du produit ABIN7448728

Cet anticorps Lapin Polyclonal détecte spécifiquement PML dans IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour PML anticorps (AA 375-425) (ABIN7448728)

Antigène: PML (Promyelocytic Leukemia (PML))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PML est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-PML anticorps

Épitope: AA 375-425

Fonction: Rabbit anti-PML IHC Antibody, Affinity Purified

Homologie: Orangutan,Gorilla,Chimpanzee,Bornean orangutan,White-tufted-ear marmoset,Pygmy chimpanzee,Primates

Purification: Affinity Purified

Immunogène: Between AA 375 and 425

Isotype: IgG

Information d'application

Indications d'application: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PML

Antigène: PML (Promyelocytic Leukemia (PML))

Autre désignation: PML

Sujet: Background: PML is a member of RBCC/TRIM family of proteins that possess a RING finger domain, B-box, and coiled-coil domain. PML is a multifunctional protein involved in activities such as tumor growth suppression, hematopoietic differentiation, gene transcription, apoptotic induction, and viral immunity. PML is often involved in chromosomal translocations with the retinoic acid receptor alpha gene. PML-retinoic acid receptor translocations are associated with acute promyelocytic leukemia.

ID gène: 5371

NCBI Accession: NP_150241

UniProt: P29590

Pathways: Signalisation p53, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus