Aurora Kinase B anticorps (C-Term)

N° du produit ABIN7448917

Cet anticorps Lapin Polyclonal détecte spécifiquement Aurora Kinase B dans IHC et IF/ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour Aurora Kinase B anticorps (C-Term) (ABIN7448917)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Détail du produit anti-Aurora Kinase B anticorps

Épitope: C-Term

Fonction: Rabbit anti-Aurora B IHC Antibody, Affinity Purified

Homologie: Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque

Purification: Affinity Purified

Immunogène: Between AA 300 and C-term

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:100 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: Aurora B

Sujet: Background: Aurora B is the central enzymatic unit of the chromosomal passenger complex (CPC). In the CPC, Aurora B is associated with the passenger proteins inner centromeric protein (INCENP), survivin, and borealin. Aurora B is a serine-threonine protein kinase essential for chromosome segregation and cytokinesis. Specific roles for Aurora B have been demonstrated in cohesin dissociation from centromeres as well as condensin I binding to chromatin.F112. Substrates of Aurora B kinase activity include desmin, septin 1, INCENP, RAC GTPase activating protein 1, and centromeric protein A.

ID gène: 9212

NCBI Accession: NP_004208

UniProt: Q96GD4

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades