CENPF anticorps (AA 2350-2400)

N° du produit ABIN7448938

Détail du produit anti-CENPF anticorps

Antigène: CENPF (Centromere Protein F (CENPF))

Épitope: AA 2350-2400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPF est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Fonction: Rabbit anti-CENP-F/Mitosin IHC Antibody, Affinity Purified

Homologie: Orangutan,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogène: Between AA 2350 and 2400

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CENPF

Antigène: CENPF (Centromere Protein F (CENPF))

Autre désignation: CENP-F/Mitosin (CENPF Produits)

Synonymes: anticorps LOC100222985, anticorps 6530404A22Rik, anticorps AI325968, anticorps CENF, anticorps Lek1, anticorps PRO1779, anticorps mitosin, anticorps im:7140452, anticorps im:7144238, anticorps im:7154719, anticorps im:7156761, anticorps si:ch211-152h14.2, anticorps hcp-1, anticorps CMF1, anticorps centromere protein F, anticorps CENPF, anticorps Cenpf, anticorps cenpf

Sujet: Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.

ID gène: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2