NPM1 anticorps (AA 250-294)

N° du produit ABIN7448992

Cet anticorps Lapin Polyclonal détecte spécifiquement NPM1 dans IHC et IF (p). Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour NPM1 anticorps (AA 250-294) (ABIN7448992)

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPM1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NPM1 anticorps

Épitope: AA 250-294

Fonction: Rabbit anti-NPM1 IHC Antibody, Affinity Purified

Homologie: Rat,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Crab-eating macaque,Northern white-cheeked gibbon,Naked mole rat,Chinese hamster,Small-eared galago

Purification: Affinity Purified

Immunogène: Between AA 250 and 294

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NPM1

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Autre désignation: NPM1

Sujet: Background: Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia [taken from the Universal Protein Resource (UniProt) P06748].

ID gène: 4869

NCBI Accession: NP_002511

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly