NPM1 anticorps (AA 250-294)

N° du produit ABIN7448992

Cet anticorps Lapin Polyclonal détecte spécifiquement NPM1 dans IHC et IF (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour NPM1 anticorps (AA 250-294) (ABIN7448992)

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPM1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-NPM1 anticorps

Épitope: AA 250-294

Fonction: Rabbit anti-NPM1 IHC Antibody, Affinity Purified

Homologie: Rat,Bovine,Dog,Horse,Rabbit,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Crab-eating macaque,Northern white-cheeked gibbon,Naked mole rat,Chinese hamster,Small-eared galago

Purification: Affinity Purified

Immunogène: Between AA 250 and 294

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NPM1

Antigène: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Autre désignation: NPM1

Sujet: Background: Nucleophosmin (NPM1) is involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. It associates with nucleolar ribonucleoprotein structures and binds single-stranded nucleic acids. NPM1 binds ribosomes presumably to drive ribosome nuclear export. Chromosomal aberrations involving NPM1 have been identified in several types of leukemia [taken from the Universal Protein Resource (UniProt) P06748].

ID gène: 4869

NCBI Accession: NP_002511

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly