PCNA anticorps (C-Term)

N° du produit ABIN7448997

Cet anticorps anti-PCNA est un anticorps Lapin Polyclonal détectant PCNA dans IHC et IF (p). Adapté pour Humain et Souris.

Aperçu rapide pour PCNA anticorps (C-Term) (ABIN7448997)

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCNA est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PCNA anticorps

Épitope: C-Term

Fonction: Rabbit anti-PCNA IHC Antibody, Affinity Purified

Homologie: Rat,Sheep,Bovine,Dog,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Crab-eating macaque,Small-eared galago,Little brown bat,Chinese hamster,Naked mole rat

Purification: Affinity Purified

Immunogène: Between AA 225 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PCNA

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Autre désignation: PCNA

Sujet: Background: PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

ID gène: 5111

NCBI Accession: NP_002583

UniProt: P12004

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy