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BRCA1 anticorps (AA 700-750)

Cet anticorps anti-BRCA1 est un anticorps Lapin Polyclonal détectant BRCA1 dans IHC et IP. Adapté pour Humain.
N° du produit ABIN7449153

Aperçu rapide pour BRCA1 anticorps (AA 700-750) (ABIN7449153)

Antigène

Voir toutes BRCA1 Anticorps
BRCA1 (Breast Cancer 1 (BRCA1))

Reactivité

  • 212
  • 36
  • 27
  • 3
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 169
  • 50
  • 2
Lapin

Clonalité

  • 173
  • 48
Polyclonal

Conjugué

  • 89
  • 19
  • 10
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Cet anticorp BRCA1 est non-conjugé

Application

  • 120
  • 58
  • 54
  • 41
  • 40
  • 38
  • 26
  • 25
  • 25
  • 16
  • 13
  • 10
  • 9
  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • Épitope

    • 33
    • 21
    • 16
    • 15
    • 15
    • 12
    • 12
    • 10
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 700-750

    Fonction

    Rabbit anti-BRCA1 Antibody, Affinity Purified

    Homologie

    Gorilla,Chimpanzee

    Purification

    Affinity Purified

    Immunogène

    between AA 700 and 750

    Isotype

    IgG
  • Indications d'application

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    Restrictions

    For Research Use only
  • Concentration

    1000 μg/mL

    Buffer

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Date de péremption

    12 months
  • Antigène

    BRCA1 (Breast Cancer 1 (BRCA1))

    Autre désignation

    BRCA1

    Sujet

    Background: BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

    ID gène

    672

    NCBI Accession

    NP_009225

    UniProt

    P38398

    Pathways

    Cycle Cellulaire, Réparation de l'ADN, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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