Recombinant PD-L1 anticorps (AA 19-239)

N° du produit ABIN7449160

Cet anticorps Lapin Monoclonal détecte spécifiquement PD-L1 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour Recombinant PD-L1 anticorps (AA 19-239) (ABIN7449160)

Antigène: PD-L1 (CD274 (PD-L1))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-L1 est non-conjugé

Application: Western Blotting (WB)

Clone: BLR226K

Détail du produit anti-PD-L1 anticorps

Épitope: AA 19-239

Fonction: Rabbit anti-PD-L1 Recombinant Monoclonal Antibody [BLR226K]

Immunogène: residues 19-239 (ECD)

Isotype: IgG

Information d'application

Indications d'application: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PD-L1

Antigène: PD-L1 (CD274 (PD-L1))

Autre désignation: PD-L1

Sujet: Background: PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)].

ID gène: 60533

NCBI Accession: NP_068693

UniProt: Q9EP73

Pathways: Cancer Immune Checkpoints