MCM2 anticorps (pSer41)
Aperçu rapide pour MCM2 anticorps (pSer41) (ABIN7449367)
Antigène
Voir toutes MCM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer41
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Fonction
- Rabbit anti-Phospho MCM2 (S41) Antibody, Affinity Purified
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Homologie
- X. laevis,X. tropicalis
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Purification
- Affinity Purified
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Immunogène
- surrounding serine 41
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Isotype
- IgG
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Indications d'application
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:5,000 - 1:20,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))
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Autre désignation
- MCM2
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Sujet
- Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM2 interacts with the core MCM complex (MCM4, 6, and 7) to regulate its helicase activity.
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ID gène
- 4171
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NCBI Accession
- NP_004517
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UniProt
- P49736
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Pathways
- Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Antigène
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