Recombinant PCNA anticorps (AA 225-261)

N° du produit ABIN7449543

Cet anticorps anti-PCNA est un anticorps Lapin Monoclonal détectant PCNA dans WB, IHC, IF (p) et ICC. Adapté pour Humain.

Aperçu rapide pour Recombinant PCNA anticorps (AA 225-261) (ABIN7449543)

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PCNA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC)

Clone: BLR075G

Détail du produit anti-PCNA anticorps

Épitope: AA 225-261

Fonction: Rabbit anti-PCNA Recombinant Monoclonal Antibody [BLR075G]

Immunogène: between AA 225 and 261 (C-term)

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 10 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PCNA

Antigène: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Autre désignation: PCNA

Sujet: Background: PCNA (Proliferating Cell Nuclear Antigen) was first identified as a factor expressed in the nuclei of replicating cells. PCNA plays a role in both DNA synthesis and repair. PCNA functions as a processivity factor for DNA polymerase by acting as a DNA clamp that tethers the polymerase catalytic units to the DNA template. The structure of PCNA is that of a trimeric ring that encircles and slides along replicating DNA. PCNA interacts with and is regulated by several proteins involved in cell cycle control and check point processes.

ID gène: 5111

NCBI Accession: NP_002583

UniProt: P12004

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy