MTA2 anticorps (AA 500-550)

N° du produit ABIN7449600

Cet anticorps anti-MTA2 est un anticorps Lapin Polyclonal détectant MTA2 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour MTA2 anticorps (AA 500-550) (ABIN7449600)

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MTA2 anticorps

Épitope: AA 500-550

Fonction: Rabbit anti-MTA2 Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 500 and 550

Isotype: IgG

Information d'application

Indications d'application:

IP: 1 - 4 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MTA2

Antigène: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Autre désignation: MTA2

Sujet: Background: MTA2 (metastasis-associated protein 2) is a component of the NuRD (nucleosome remodeling and histone deacetylation) complex. MTA2 is highly similar to MTA1 and was identified as a factor differentially expressed in a carcinoma cell line. MTA2 can repress p53-dependent transcriptional activation by enhancing its deacetylation. MTA1 has also been shown to function as a corepressor for ligand-induced estrogen receptor (ER) transactivation. As part of the NuRD complex MTA2 represses ERalpha transactivation activity by modulating the acetylation status of ERalpha.

ID gène: 9219

NCBI Accession: NP_004730

UniProt: O94776

Pathways: Chromatin Binding