SLBP anticorps (AA 220-270)

N° du produit ABIN7449822

Cet anticorps anti-SLBP est un anticorps Lapin Polyclonal détectant SLBP dans WB et IP. Adapté pour Humain.

Aperçu rapide pour SLBP anticorps (AA 220-270) (ABIN7449822)

Antigène: SLBP (Stem-Loop Binding Protein (SLBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLBP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-SLBP anticorps

Épitope: AA 220-270

Fonction: Rabbit anti-SLBP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 220 and 270

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SLBP

Antigène: SLBP (Stem-Loop Binding Protein (SLBP))

Autre désignation: SLBP

Sujet: Background: Stem-loop-binding protein (SLBP) is an RNA-binding protein involved in the histone pre-mRNA processing. SLBP binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). SLBP plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. It stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. It is also involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. SLBP binds to the 5' side of the stem-loop structure of histone pre-mRNAs [taken from the Universal Protein Resource (UniProt) Q14493].

ID gène: 7884

NCBI Accession: NP_006518

UniProt: Q14493