Girdin anticorps (AA 1425-1475)

N° du produit ABIN7450080

Cet anticorps anti-Girdin est un anticorps Lapin Polyclonal détectant Girdin dans WB et IP. Adapté pour Humain.

Aperçu rapide pour Girdin anticorps (AA 1425-1475) (ABIN7450080)

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Girdin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Girdin anticorps

Épitope: AA 1425-1475

Fonction: Rabbit anti-CCDC88A Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: between AA 1425 and 1475

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Girdin

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Autre désignation: CCDC88A

Sujet: Background: CCDC88A encodes the protein known as GIV (G alpha-interacting vesicle-associated protein) and Girdin. CCDC88A plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. CCDC88A Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. CCDC88A has also been found to be essential for the integrity of the actin cytoskeleton and for cell migration. It is required for formation of actin stress fibers and lamellipodia, and it may be involved in membrane sorting in the early endosome [taken from the Universal Protein Resource (UniProt) Q3V6T2].

ID gène: 55704

NCBI Accession: NP_001129069

UniProt: Q3V6T2